Rautenschlein S, Neumann U
Clinic for Poultry, School of Veterinary Medicine in Hannover, Bunteweg 17, 30559 Hannover, Germany.
Pol J Vet Sci. 2004;7(1):39-46.
Knowledge of the potential, but also of the vulnerability of the avian immune system is not only of academic interest. The intact immune system, beginning in the embryo, is of central significance to safeguarding health and productivity in poultry flocks. Interactions between cellular and soluble constituents of the avian immune system on one hand, and the nature of immunosuppressants on the other, determine whether the avian immune system is able to cope with microbial and non-microbial challenges. Modulation of the immune response can be achieved in the classical way by specific vaccinations or possibly in the future by DNA vaccination. Cytokine inducing compounds may provide additional tools to enhance immune reactivity. The future will tell whether these approaches will be applicable in disease preventation or treatment in poultry medicine. In concert with these tools, however, strict hygiene measures from incubation until production, slaughter and processing are equally of vital significance as part of disease prevention strategies, ultimately leading to high quality food products originating from animal production.
了解禽类免疫系统的潜能及其脆弱性，不仅具有学术价值。从胚胎期开始的完整免疫系统，对于保障家禽群的健康和生产力至关重要。一方面，禽类免疫系统的细胞成分与可溶性成分之间的相互作用，另一方面，免疫抑制剂的性质，决定了禽类免疫系统是否能够应对微生物和非微生物的挑战。免疫反应的调节可以通过传统的特异性疫苗接种来实现，或者未来可能通过DNA疫苗接种来实现。细胞因子诱导化合物可能为增强免疫反应性提供额外的工具。未来将证明这些方法是否适用于家禽医学的疾病预防或治疗。然而，与这些工具协同作用的是，从孵化到生产、屠宰和加工的严格卫生措施，作为疾病预防策略的一部分同样至关重要，最终生产出源自动物生产的高质量食品。
