Méary R, Danan J P, Tomeno B, Forest M, Cirotteau Y
Rev Chir Orthop Reparatrice Appar Mot. 1978 Apr-May;64(3):195-204.
The authors have treated nineteen cases of desmoid fibroma of the limbs of which two were intraosseous. The severity of the lesion was greater when sited proximally in the limbs. In many patients, the tumours grew slowly and gave little incapacity. A large number of recurrences were found after surgical excision. The treatment, however, must be based on surgical excision which should be as extensive as possible. Radiotherapy should only be used after the tumour has recurred several times. In view of reports of spontaneous healing, hormone therapy was tried but no conclusions could be drawn from these trials.
作者治疗了19例肢体硬纤维瘤,其中2例为骨内硬纤维瘤。病变位于肢体近端时严重程度更高。许多患者中,肿瘤生长缓慢,功能障碍轻微。手术切除后发现大量复发情况。然而,治疗必须基于尽可能广泛的手术切除。仅在肿瘤多次复发后才应使用放疗。鉴于有自发愈合的报道,尝试了激素治疗,但这些试验未能得出结论。