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母马子宫复旧期间血浆中13,14-二氢-15-酮前列腺素F2α的浓度。

Plasma concentrations of 13,14-dihydro-15-ketoprostaglandin F2 alpha in mares during uterine involution.

作者信息

Sertich P L, Watson E D

机构信息

Secretion of Reproductive Studies, School of Veterinary Medicine, University of Pennsylvania, Kennett Square 19348.

出版信息

J Am Vet Med Assoc. 1992 Aug 1;201(3):434-7.

PMID:1506246
Abstract

Twelve mares were allowed to foal naturally, after which they were monitored to study uterine involution. Starting on day 3 after parturition, the internal genital tract was examined per rectum manually and ultrasonographically every other day for changes in uterine characteristics and ovarian activity. By day 5, gravid and nongravid uterine horns were similar in size, and by day 7, uterine fluid was absent. On day 7 after parturition, endometrial biopsy samples were obtained for histologic evaluation, and uterine swab specimens were obtained for microbiologic culture. Uterine swab specimens from 10 of 12 mares had slight bacterial growth. The uteri of 8 of the 12 mares were histologically involuted by day 7. All mares ovulated 7 to 12 days after parturition. Concentrations of 13,14-dihydro-15-keto-PGF2 alpha (PGFM) were measured in jugular plasma samples obtained daily for 21 days after parturition. Concentrations of PGFM were low by the day after parturition, and there was no significant correlation between uterine involution and PGFM concentrations in these mares. All 12 mares were bred at the first estrus after parturition, and 9 became pregnant.

摘要

12匹母马自然分娩后,对其进行监测以研究子宫复旧情况。从分娩后第3天开始,每隔一天通过直肠触诊和超声检查内生殖道,观察子宫特征和卵巢活动的变化。到第5天,妊娠子宫角和非妊娠子宫角大小相似,到第7天,子宫内无积液。分娩后第7天,采集子宫内膜活检样本进行组织学评估,并采集子宫拭子样本进行微生物培养。12匹母马中有10匹的子宫拭子样本有轻微细菌生长。12匹母马中有8匹的子宫在第7天时组织学上已复旧。所有母马在分娩后7至12天排卵。在分娩后21天内,每天采集颈静脉血浆样本,测定13,14-二氢-15-酮-PGF2α(PGFM)的浓度。分娩后次日PGFM浓度较低,这些母马的子宫复旧与PGFM浓度之间无显著相关性。所有12匹母马在分娩后的第一次发情期配种,9匹受孕。

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