Higenbottam Tim, Laude Liz, Emery Celia, Essener Mohamed
Division of Clinical Science (South), Medical School, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2RX, UK.
Clin Chest Med. 2004 Mar;25(1):123-31. doi: 10.1016/S0272-5231(03)00133-3.
Pulmonary hypertension, as a result of adverse drug reactions, must be considered as a rare occurrence. With good medicinal chemistry and screening of compounds before entry into man, it should be almost totally avoidable. Life and medicine are a continuing challenge as our exploration of the regions of unknown biology throw up new targets and new mechanisms and may catch us again as the anorectic (anorectic) drug caught our predecessors.
药物不良反应导致的肺动脉高压必须被视为一种罕见情况。通过良好的药物化学研究以及在人体试验前对化合物进行筛选，这种情况应该几乎完全可以避免。随着我们对未知生物学领域的探索不断涌现新的靶点和新的机制，生命与医学面临着持续的挑战，而且我们可能会像食欲抑制剂曾让我们的前辈们遭遇问题那样再次陷入困境。
