Sabik Joseph F, Nemeh Hassan, Lytle Bruce W, Blackstone Eugene H, Gillinov A Marc, Rajeswaran Jeevanantham, Cosgrove Delos M
Department of Thoracic and Cardiovascular Surgery and Biostatistics and Epidemiology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Ann Thorac Surg. 2004 Apr;77(4):1315-20. doi: 10.1016/j.athoracsur.2003.08.056.
The axillary artery is our preferred arterial cannulation site when the ascending aorta cannot be cannulated. Previously, we cannulated the artery directly; now we use a side graft. The purposes of this study were to (1) investigate cannulation-related morbidity and (2) determine whether use of a side graft reduces it.
From January 1993 to January 2001, 392 patients underwent 399 axillary artery cannulations. Indications included calcified ascending aorta (129, 32%), ascending aortic aneurysm (115, 29%), type I aortic dissection (85, 21%), cardiac reoperation (70, 18%), and calcified femoral artery (26, 6%). The axillary artery was cannulated directly in 212 (53%) and with a side graft in 187 (47%). Comparisons of cannulation-related morbidity between the direct cannulation and side graft groups were made overall and after both adjusting and matching for propensity score.
Cannulation-related morbidity was infrequent, with brachial plexus injury in 7 (1.8%), axillary artery damage in 7 (1.8%), aortic dissection in 3 (0.8%), and arm ischemia in 3 (0.8%). Only 4 of 187 (2.1%) occurred in the side graft group, versus 16 of 212 (7.0%) with direct cannulation (p = 0.03). After propensity adjustment, the odds ratio for reduction of risk of cannulation-related morbidity with use of a side graft was 0.15 (p = 0.002).
Use of the axillary artery as inflow for cardiopulmonary bypass is associated with low morbidity. However, cannulation with a side graft was associated with less cannulation-related morbidity than direct cannulation. Routine use of a side graft is recommended whenever axillary artery cannulation is indicated.
当无法对升主动脉进行插管时,腋动脉是我们首选的动脉插管部位。以前,我们直接对该动脉进行插管;现在我们使用侧支移植物。本研究的目的是:(1)调查与插管相关的发病率;(2)确定使用侧支移植物是否能降低发病率。
从1993年1月至2001年1月,392例患者接受了399次腋动脉插管。适应证包括升主动脉钙化(129例,32%)、升主动脉瘤(115例,29%)、I型主动脉夹层(85例,21%)、心脏再次手术(70例,18%)以及股动脉钙化(26例,6%)。212例(53%)采用直接腋动脉插管,187例(47%)采用侧支移植物插管。对直接插管组和侧支移植物组的插管相关发病率进行了总体比较,并在调整和匹配倾向评分后进行了比较。
插管相关的发病率较低,臂丛神经损伤7例(1.8%),腋动脉损伤7例(1.8%),主动脉夹层3例(0.8%),手臂缺血3例(0.8%)。187例中只有4例(2.1%)发生在侧支移植物组,而直接插管组212例中有16例(7.0%)(p = 0.03)。倾向调整后,使用侧支移植物降低插管相关发病风险的优势比为0.15(p = 0.00)。
使用腋动脉作为体外循环的流入道发病率较低。然而,与直接插管相比,使用侧支移植物插管的相关发病率更低。只要有腋动脉插管指征,建议常规使用侧支移植物。