Craig Joseph G, Cody Dianna D, Van Holsbeeck Marnix
Department of Radiology, Henry Ford Hospital, 2799 West Grand Blvd., Detroit, MI 48202, USA.
Skeletal Radiol. 2004 Jun;33(6):337-44. doi: 10.1007/s00256-003-0734-x. Epub 2004 Apr 3.
To explore how the size of the growth plate changes with age using three-dimensional (3D) models of the distal femoral and proximal tibial growth plates in pediatric patients.
We retrospectively created 3D models of the normal unaffected distal femoral (n=20) and proximal tibial (n=10) growth plates in 14 patients (9 males, 5 females) age range 3.8-15.6 years who were referred for evaluation of premature partial closure of the growth plate or hyaline cartilage abnormality. All patients had one or more 3D fat-suppressed spoiled GRASS sequence from which models were made of normal growth plates. Total projected area was estimated from standardized maximum intensity projection (MIP) views, and volume was computed from the entire model. We also included the total projected area of the distal femur (n=7) or proximal tibia (n=8) in 11 patients (8 males, 3 females, 5-13 years) who had previously been evaluated for bone bridging.
The 3D femoral and tibial growth plate anatomy was displayed. Femoral growth plate area varied from 804 mm2 to 3,463 mm2. Femoral physeal cartilage volume varied from 2.1 cm3 to 12.6 cm3. Tibial growth plate area varied from 736 mm2 to 3,026 mm2. Tibial physeal cartilage volume varied from 1.9 cm3 to 13.2 cm3. The growth plate area values appear to increase linearly with increasing age.
The distal femoral and proximal tibial physeal plates have complex anatomy. Both area and volume of the growth plates appeared to follow a linear increase with age and reached a plateau in adolescence, although there was some scatter. Area appears to have less measurement variability than volume, and may be a more reliable predictor of growth plate tissue quantity.
利用儿科患者股骨远端和胫骨近端生长板的三维（3D）模型，探讨生长板大小如何随年龄变化。
我们回顾性地创建了14例患者（9例男性，5例女性）正常未受影响的股骨远端（n = 20）和胫骨近端（n = 10）生长板的3D模型，这些患者年龄在3.8 - 15.6岁之间，因生长板过早部分闭合或透明软骨异常而前来评估。所有患者均有一个或多个3D脂肪抑制扰相梯度回波序列，据此制作正常生长板的模型。从标准化最大强度投影（MIP）视图估计总投影面积，并从整个模型计算体积。我们还纳入了11例患者（8例男性，3例女性，年龄5 - 13岁）股骨远端（n = 7）或胫骨近端（n = 8）的总投影面积，这些患者此前已接受骨桥接评估。
展示了3D股骨和胫骨生长板的解剖结构。股骨生长板面积从804平方毫米到3463平方毫米不等。股骨骨骺软骨体积从2.1立方厘米到12.6立方厘米不等。胫骨生长板面积从736平方毫米到3026平方毫米不等。胫骨骨骺软骨体积从1.9立方厘米到13.2立方厘米不等。生长板面积值似乎随年龄增长呈线性增加。
股骨远端和胫骨近端骨骺板具有复杂的解剖结构。生长板的面积和体积似乎均随年龄呈线性增加，并在青春期达到稳定水平，尽管存在一些离散度。面积的测量变异性似乎比体积小，可能是生长板组织量更可靠的预测指标。
