Nishimaki Shigeru, Endo Masaya, Seki Kazuo, Yokota Shumpei
Department of Pediatrics, Yokohama City University School of Medicine, Yokohama, Kanagawa, Japan.
Prenat Diagn. 2004 Apr;24(4):257-9. doi: 10.1002/pd.846.
To describe a case of hemimegalencephaly misdiagnosed prenatally.
We presented a neonate with hemimegalencephaly, who was thought to have a congenital brain tumor by fetal cerebral ultrasonography. Postnatal MRI findings showed hemimegalencephaly characterized by mild enlargement of the affected hemisphere with a predominantly abnormal signal in the frontal lobe. The appearance of an echogenic round-shaped mass may have resulted from predominant hypermyelination and/or dysplastic neural/glial tissue in the frontal white matter.
In prenatal diagnosis with fetal cerebral ultrasonography, it is difficult to distinguish between congenital brain tumor and hemimegalencephaly in which enlargement of the hemisphere is mild and the affected area of the brain is localized or predominantly in part of a cerebral hemisphere.
描述一例产前误诊的半侧巨脑症病例。
我们报告了一名患有半侧巨脑症的新生儿，其在胎儿脑部超声检查时被认为患有先天性脑肿瘤。产后磁共振成像（MRI）结果显示为半侧巨脑症，其特征为患侧半球轻度增大，额叶主要呈异常信号。额叶白质中回声增强的圆形肿块的出现可能是由于髓鞘过度形成和/或神经/神经胶质组织发育异常所致。
在胎儿脑部超声产前诊断中，对于半球轻度增大且脑部受累区域局限或主要位于大脑半球某一部分的先天性脑肿瘤和半侧巨脑症，难以进行区分。
