Fröjdh Karin, Håkansson Anders, Karlsson Ingvar
Research and Development Unit for Primary Health Care, Vårdcentralen Kronoparken, Karlstad, Sweden.
Int J Geriatr Psychiatry. 2004 Apr;19(4):386-90. doi: 10.1002/gps.1102.
No depression rating scale has yet been designed to identify all clinically important depressive states in elderly. Therefore, this study investigated the Hopkins Symptom Checklist-25 (HSCL-25), a self-rating scale for depression, to see if it was a sensitive indicator of major, minor and subsyndromal depression.
Structured interviews of 37 people with a high depressive score and an age and sex matched control group comprised of 37 persons with a low depressive score in HSCL-25, in order to compare the HSCL-25 ratings with the Montgomery-Asberg-Depression Rating Scale (MADRS) as well as with the criteria for major, minor and subsyndromal depression.
The sensitivity for identifying any depression was 94% and the specificity was 94% for HSCL-25 compared to the diagnostic criteria for depressive disorders.
HSCL-25 is a sensitive case-finder of any depressive disorder and may be useful in general practice and for screening studies of depression in elderly people.
目前尚无专门设计用于识别老年人所有具有临床重要意义的抑郁状态的抑郁评定量表。因此，本研究对霍普金斯症状清单-25（HSCL-25）这一抑郁自评量表进行了调查，以确定它是否是重度、轻度和亚综合征性抑郁的敏感指标。
对37名抑郁得分高的人以及由37名HSCL-25抑郁得分低的人组成的年龄和性别匹配的对照组进行结构化访谈，以便将HSCL-25评分与蒙哥马利-阿斯伯格抑郁评定量表（MADRS）以及重度、轻度和亚综合征性抑郁的标准进行比较。
与抑郁障碍的诊断标准相比，HSCL-25识别任何抑郁的敏感性为94%，特异性为94%。
HSCL-25是任何抑郁障碍的敏感病例筛查工具，可能在全科医疗以及老年人抑郁筛查研究中有用。
