[Study status of collagen-based biomaterials in drug release and tissue engineering].

OBJECTIVE

To introduce the development of the collagen materials in drug release and tissue engineering.

METHODS

Literature review and complex analysis were adopted.

RESULTS

In recent years, some good progress has been made in the studies of collagen, and study on collagen-based materials has become an investigative hotspot especially in tissue engineering. Some new collagen-based drug delivery and engineered materials have come into clinically-demonstrated moment, which will promote their clinical applications in tissue repairs.

CONCLUSION

Collagen has been considered a good potential material in drug release, especially in the tissue-engineering field. To give collagen new characters we should pay more attention to grafting with different function branches through chemistry technique in the future work, except moderate cross-linking treatment or commingling with other nature or synthesized macromolecules.