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一例局限于小腿的结节性多动脉炎,在特发性肺纤维化之前出现高滴度的髓过氧化物酶抗中性粒细胞胞浆抗体。

A case of polyarteritis nodosa limited to lower legs with a high titer of MPO-ANCA under precedence of idiopathic pulmonary fibrosis.

作者信息

Sugisaki Kota, Takeda Isao, Kanno Takashi, Oguchi Yoshihito, Kasukawa Reiji

机构信息

Division of Rheumatology, Ohta Nishinouchi Hospital, Koriyama, Japan.

出版信息

Fukushima J Med Sci. 2003 Dec;49(2):141-8. doi: 10.5387/fms.49.141.

DOI:10.5387/fms.49.141
PMID:15065640
Abstract

A 58-year-old man with a 15-year history of idiopathic pulmonary fibrosis was hospitalized for rapid progression of muscle weakness to bilateral foot drop. Although laboratory data revealed high titers of myeloperoxidase anti-neutrophil cytoplasmic antibody (489 EU), the patient was diagnosed as polyarteritis nodosa limited to the lower portions of the legs. Despite of the treatment with large doses of corticosteroids and cyclosporin A, his symptoms barely improved during the following two months.

摘要

一名患有特发性肺纤维化15年的58岁男性因肌肉无力迅速进展至双侧足下垂而住院。尽管实验室检查数据显示髓过氧化物酶抗中性粒细胞胞浆抗体滴度很高(489 EU),但该患者被诊断为局限于双下肢的结节性多动脉炎。尽管给予了大剂量皮质类固醇和环孢素A治疗,但在接下来的两个月里他的症状几乎没有改善。

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A case of polyarteritis nodosa limited to lower legs with a high titer of MPO-ANCA under precedence of idiopathic pulmonary fibrosis.一例局限于小腿的结节性多动脉炎,在特发性肺纤维化之前出现高滴度的髓过氧化物酶抗中性粒细胞胞浆抗体。
Fukushima J Med Sci. 2003 Dec;49(2):141-8. doi: 10.5387/fms.49.141.
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引用本文的文献

1
A case of MPO-ANCA-positive polyarteritis nodosa complicated by exudative otitis media, mononeuritis multiplex, and acute renal failure.一例 MPO-ANCA 阳性多动脉炎合并渗出性中耳炎、多发性单神经炎和急性肾衰竭。
Clin Exp Nephrol. 2011 Oct;15(5):754-760. doi: 10.1007/s10157-011-0457-6. Epub 2011 May 26.