高压氧疗法对软组织感染疗程的影响。
The effect of hyperbaric oxygen therapy on the bout of treatment for soft tissue infections.
作者信息
Sugihara Atsushi, Watanabe Hironobu, Oohashi Motoki, Kato Naoki, Murakami Hideaki, Tsukazaki Satoshi, Fujikawa Kyosuke
机构信息
Department of Orthopaedic Surgery, National Defense Medical College, 3-2 Namiki, Tokorozawa City, Saitama 359-8513, Japan.
出版信息
J Infect. 2004 May;48(4):330-3. doi: 10.1016/j.jinf.2004.01.019.
OBJECTIVES
Hyperbaric oxygen (HBO) therapy is often combined with antibiotic therapy for infections such as gas gangrene and osteomyelitis. Although numerous investigations have been undertaken to assess the effect of adjunctive HBO therapy on the treatment of infections, the bout of treatment has not been referred in the previous investigations. The purpose of this retrospective study was to evaluate the efficacy of HBO therapy on the bout of treatment for soft tissue infections.
PATIENTS AND METHODS
In the period between 1994 and 2001, we treated 23 patients with soft tissue infections. Nine patients were treated with antibiotic chemotherapy alone, and 14 patients were treated with a combination of antibiotic chemotherapy and HBO therapy. The mean bout of treatment was compared between these two groups.
RESULTS
The mean bout treated with a combination of antibiotic and HBO was significantly shorter than that with antibiotic alone.
CONCLUSION
Our result indicates that HBO therapy combined with antibiotic therapy is able to shorten the bout of treatment for soft tissue infections. Therefore, we recommend HBO therapy combined with antibiotic therapy for soft tissue infections.
目的
高压氧（HBO）疗法常与抗生素疗法联合用于治疗气性坏疽和骨髓炎等感染。尽管已经进行了大量研究来评估辅助HBO疗法对感染治疗的效果，但之前的研究中并未提及治疗疗程。这项回顾性研究的目的是评估HBO疗法对软组织感染治疗疗程的疗效。
患者与方法
在1994年至2001年期间，我们治疗了23例软组织感染患者。9例患者仅接受抗生素化疗，14例患者接受抗生素化疗与HBO疗法联合治疗。比较了这两组的平均治疗疗程。
结果
抗生素与HBO联合治疗的平均疗程明显短于单纯使用抗生素治疗的疗程。
结论
我们的结果表明，HBO疗法联合抗生素疗法能够缩短软组织感染的治疗疗程。因此，我们推荐HBO疗法联合抗生素疗法用于治疗软组织感染。
Zotero 插件