慢性炎症性脱髓鞘性多发性神经病中神经卡压性病变的发生情况。
Occurrence of nerve entrapment lesion in chronic inflammatory demyelinating polyneuropathy.
作者信息
Padua L, Caliandro P, Aprile I, Sabatelli M, Madia F, Tonali P
机构信息
Institute of Neurology, Catholic University, L.go F. Vito 1, 00168 Rome, Italy.
出版信息
Clin Neurophysiol. 2004 May;115(5):1140-4. doi: 10.1016/j.clinph.2003.12.007.
OBJECTIVE
To evaluate the occurrence of nerve entrapment syndrome in chronic inflammatory demyelinating polyneuropathy (CIDP).
METHODS
We retrospectively evaluated neurophysiologic results of 41 (25 male and 16 female, mean age 49.8, range 11-87) patients with CIDP. We evaluated the frequency of focal neurophysiologic lesion at entrapment site distinguishing two kinds of lesion: (a) true entrapment; and (b) false entrapment on the basis of nerve conduction results.
RESULTS
Occurrence of focal aggression within the entrapment site is similar to that out of the entrapment site in all examined nerves.
CONCLUSIONS
The entrapment sites are not an elective zone of focal autoimmune aggression in CIDP. Therefore, in CIDP patients a true entrapment, neurophysiologically demonstrated, could be a concomitant pathology and if a severe and persistent entrapment worsens functional deficit and symptoms, a surgical decompression could be useful.
目的
评估慢性炎症性脱髓鞘性多发性神经病（CIDP）中神经卡压综合征的发生率。
方法
我们回顾性评估了41例（25例男性和16例女性，平均年龄49.8岁，范围11 - 87岁）CIDP患者的神经生理学结果。我们根据神经传导结果区分两种病变，评估卡压部位局灶性神经生理学病变的频率：（a）真性卡压；（b）假性卡压。
结果
在所有检查的神经中，卡压部位内局灶性侵犯的发生率与卡压部位外相似。
结论
在CIDP中，卡压部位不是局灶性自身免疫侵犯的选择性区域。因此，在CIDP患者中，经神经生理学证实的真性卡压可能是一种伴随病变，如果严重且持续的卡压使功能缺损和症状恶化，手术减压可能有用。
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