运用捕获-再捕获法估算台湾地区婴儿痉挛症的患病率和发病率。
Estimation of prevalence and incidence of infantile spasms in Taiwan using capture-recapture method.
作者信息
Chen Chih-Chuan, Chen Ta-Fu, Lin Haung-Chi, Oon Pei-Ching, Wu Hui-Min, Wang Pen-Jung, Chen Tony Hsiu-Hsi, Liou Horng-Huei
机构信息
Department of Neurology and Pharmacology, National Taiwan University Hospital and National Taiwan University College of Medicine, No. 1, Sec 1, Jan-Ai Road, Taipei 100, Taiwan, ROC.
出版信息
Epilepsy Res. 2004 Jan;58(1):37-42. doi: 10.1016/j.eplepsyres.2003.12.003.
PURPOSE
To estimate the prevalence, incidence, and case-fatality of infantile spasms (IS) in Taiwan.
METHODS
A retrospective cohort of patients with IS was obtained from one medical center to identify 69 IS cases from 1985 to 1997. This cohort, in conjunction with the claimed data from the National Health Insurance, was used to estimate the prevalence and incidence of IS by capture-recapture design, taking the case-fatality of IS into account.
RESULTS
The prevalence rate of IS for aged 0-9 years was 0.046 per thousand. The incidence rate was estimated as 6 over 100,000 per year in Taiwan. Of the 69 IS cases, 8 deaths were ascertained. The case-fatality rate was 11.6%. The leading cause of death was status epilepticus.
CONCLUSIONS
We have demonstrated an efficient method to estimate the incidence and prevalence rates of IS in Taiwan. Our results help to make a clear understanding of the disease burden of IS in this society.
目的
评估台湾地区婴儿痉挛症（IS）的患病率、发病率及病死率。
方法
从一家医疗中心获取IS患者的回顾性队列，以确定1985年至1997年期间的69例IS病例。该队列结合国民健康保险的申报数据，采用捕获-再捕获设计来估计IS的患病率和发病率，并考虑了IS的病死率。
结果
0至9岁儿童IS的患病率为千分之0.046。台湾地区IS的发病率估计为每年十万分之六。在69例IS病例中，确定有8例死亡。病死率为11.6%。主要死亡原因是癫痫持续状态。
结论
我们展示了一种有效的方法来估计台湾地区IS的发病率和患病率。我们的结果有助于清楚了解该社会中IS的疾病负担。
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