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Cleavage of some annulated tetrahydropyridines under the action of dimethyl acetylene dicarboxylate in protic solvents. New practical route to substituted pyrroles and indoles.

作者信息

Borisova Tatiana N, Voskressensky Leonid G, Soklakova Tatiana A, Kulikova Larisa N, Varlamov Alexey V

机构信息

Organic Chemistry Department, Russian Peoples Friendship University, 6, Miklukho-Maklaya St., Moscow 117198, Russia.

出版信息

Mol Divers. 2003;6(3-4):207-12. doi: 10.1023/b:modi.0000006760.30731.46.

DOI:10.1023/b:modi.0000006760.30731.46
PMID:15068083
Abstract

Tetrahydropyrrolo[3,2-c]pyridines and tetrahydropyrido[4,3-b]indoles undergo piperidine ring opening under the action of dimethyl acetylene dicarboxylate in alcohols or in aqueous dioxane, providing beta-(alk)oxy-substituted pyrroles (indoles) in moderate to high yields.

摘要

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本文引用的文献

1
Investigation on the antiplatelet activity of pyrrolo[3,2-c]pyridine-containing compounds.含吡咯并[3,2-c]吡啶化合物的抗血小板活性研究。
J Pharm Pharmacol. 2003 Mar;55(3):323-32. doi: 10.1211/002235702676.