Garrott Helen M, Walland Mark J
Clin Exp Ophthalmol. 2004 Apr;32(2):224-6. doi: 10.1111/j.1442-9071.2004.00787.x.
Raised intraocular pressure and glaucoma have rarely been associated with use of periorbital corticosteroids for dermatological conditions such as blepharitis and eczema. Three cases are described in which periorbital topical corticosteroids appear to have resulted in raised intraocular pressure or glaucoma. Topical corticosteroids used for dermatological conditions around the face and eyes are often regarded as being fairly innocuous with regard to ocular side-effects. This case series demonstrates that secondary open-angle glaucoma can be a sight-threatening consequence, and periorbital steroids should therefore be used cautiously and sparingly, particularly in those with a family history of glaucoma. Intraocular pressure may not always return to normal upon cessation of the drug.
眼内压升高和青光眼很少与将眶周皮质类固醇用于睑缘炎和湿疹等皮肤病学状况相关。本文描述了三例眶周局部使用皮质类固醇似乎导致眼内压升高或青光眼的病例。用于面部和眼部周围皮肤病学状况的局部皮质类固醇通常被认为在眼部副作用方面相当无害。该病例系列表明,继发性开角型青光眼可能是一种威胁视力的后果,因此眶周类固醇应谨慎且少量使用,尤其是在有青光眼家族史的患者中。停药后眼内压可能并不总是恢复正常。