对英夫利昔单抗有反应的克罗恩病相关慢性复发性多灶性骨髓炎
Crohn's-associated chronic recurrent multifocal osteomyelitis responsive to infliximab.
作者信息
Carpenter Ellen, Jackson Mary Anne, Friesen Craig A, Scarbrough Marc, Roberts Charles C
机构信息
Inflammatory Bowel Disease Program, Section of Gastroenterology, The Children's Mercy Hospital and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA.
出版信息
J Pediatr. 2004 Apr;144(4):541-4. doi: 10.1016/j.jpeds.2003.12.038.
We report a case of chronic recurrent clavicular osteomyelitis in association with Crohn disease. Steroid therapy resulted in partial remission; however, intractable shoulder pain and an enlarging clavicular mass subsequently recurred. Infliximab therapy resulted in significant improvement in the degree of bone pain and resolution of the large sclerotic clavicular lesion.
我们报告一例与克罗恩病相关的慢性复发性锁骨骨髓炎病例。类固醇治疗导致部分缓解；然而，难治性肩部疼痛和不断增大的锁骨肿块随后复发。英夫利昔单抗治疗使骨痛程度显著改善，大的锁骨硬化性病变消退。
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