Precious D, Armstrong J, Morrison A, Field C
Department of Oral and Maxillofacial Surgery, Dalhousie University, Halifax, Nova Scotia, Canada.
J Oral Maxillofac Surg. 1992 Sep;50(9):956-7. doi: 10.1016/0278-2391(92)90054-4.
It is well known that long-term corticosteroid therapy can lead to avascular necrosis of the femoral head. There is suspicion among orthopedic surgeons that short-term, high-dose steroid use poses similar risks. The records of 2,773 patients (1,497 who had total hip replacement and 1,276 who had orthognathic surgery) were retrospectively reviewed. No hip replacements had been done in the orthognathic surgery group and none of the patients in the total hip replacement group had undergone orthognathic surgery. The use of short-course, systemic corticosteroids to reduce postoperative swelling in orthognathic surgery did not seem to cause avascular necrosis of the femoral head.
众所周知,长期使用皮质类固醇疗法可导致股骨头缺血性坏死。骨科医生怀疑短期大剂量使用类固醇也有类似风险。对2773例患者(1497例行全髋关节置换术,1276例行正颌手术)的记录进行了回顾性研究。正颌手术组未进行髋关节置换术,全髋关节置换组患者均未接受正颌手术。在正颌手术中使用短疗程全身性皮质类固醇以减轻术后肿胀似乎不会导致股骨头缺血性坏死。