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胸椎单骨型纤维结构不良:临床病理描述与随访。病例报告。

Monostotic fibrous dysplasia of the thoracic spine: clinopathological description and follow up. Case report.

作者信息

Arazi Mehmet, Guney Onder, Ozdemir Mustafa, Uluoglu Omer, Uzum Nuket

机构信息

Department of Orthopaedic Surgery and Traumatology, Selçuk University, Meram Medical School, Konya, Turkey.

出版信息

J Neurosurg. 2004 Apr;100(4 Suppl Spine):378-81. doi: 10.3171/spi.2004.100.4.0378.

DOI:10.3171/spi.2004.100.4.0378
PMID:15070149
Abstract

The authors report the case of a 53-year-old woman with monostotic fibrous dysplasia of the thoracic spine. The patient presented with a 1-month history of pain in the thoracic spinal region. En bloc resection of the lesion was successfully performed via a transthoracic approach, and a histopathological examination confirmed the diagnosis of fibrous dysplasia. At 24-month follow-up examination, pain and vertebral instability were absent. The findings in this case illustrate that, although very rare, monostotic fibrous dysplasia of the thoracic spine should be considered in the differential diagnosis of spinal tumors. Although a consensus for management of this disease has not been achieved, the authors recommend radical removal of all involved bone as well as internal fixation or bone graft-assisted fusion to achieve long-term stabilization.

摘要

作者报告了一例53岁患有胸椎单发性骨纤维异常增殖症的女性病例。该患者有1个月的胸椎区域疼痛病史。通过经胸入路成功地整块切除了病变,组织病理学检查确诊为骨纤维异常增殖症。在24个月的随访检查中,疼痛和椎体不稳定症状消失。该病例的研究结果表明,尽管胸椎单发性骨纤维异常增殖症非常罕见,但在脊柱肿瘤的鉴别诊断中应予以考虑。虽然对于该疾病的治疗尚未达成共识,但作者建议彻底切除所有受累骨骼,并进行内固定或骨移植辅助融合以实现长期稳定。

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引用本文的文献

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Int J Spine Surg. 2021 Feb;14(s4):S46-S51. doi: 10.14444/7164. Epub 2020 Dec 29.
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Treatment of Polyostotic Fibrous Dysplasia of the Thoracic Spine with Intravenous Pamidronate: Result from 9 Months Follow Up.静脉注射帕米膦酸治疗胸椎多骨型纤维发育不良:9个月随访结果
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Imaging diagnosis of monostotic fibrous dysplasia in thoracic and lumbar spine vertebrae.
J Huazhong Univ Sci Technolog Med Sci. 2007 Dec;27(6):684-6. doi: 10.1007/s11596-007-0617-9.