Harris Rebecca, Nicoll Alison D, Adair Pauline M, Pine Cynthia M
WHO Collaborating Centre on Oral Health in Deprived Communities, University of Liverpool Dental School, England, UK.
Community Dent Health. 2004 Mar;21(1 Suppl):71-85.
To conduct a systematic review of the literature on risk factors for dental caries in deciduous teeth of children aged six years and under, to give a scientific framework for the international collaborative studies on inequalities in childhood caries.
Accepted guidelines were followed. Studies were identified by electronic searching and reviewed on the basis of key words, title and abstract by two reviewers to assess whether inclusion criteria were met. Copies of all articles were obtained and assessed for quality according to the study design.
1029 papers were identified from the electronic search, 260 met the prima facie inclusion criteria. 183 were excluded once full copies of these papers were obtained. Of the 77 studies included, 43 were cross sectional, 19 cohort studies, 8 case control studies and 7 interventional studies. Few obtained the highest quality scores. 106 risk factors were significantly related to the prevalence or incidence of caries.
There is a shortage of high quality studies using the optimum study design, i.e. a longitudinal study. The evidence suggests that children are most likely to develop caries if Streptococcus Muttans is acquired at an early age, although this may be partly compensated by other factors such as good oral hygiene and a non-cariogenic diet. Diet and oral hygiene may interact so that if there is a balance of 'good' habits by way of maintaining good plaque control and 'bad' habits by way of having a cariogenic diet, the development of caries may be controlled.
对6岁及以下儿童乳牙龋齿危险因素的文献进行系统综述,为儿童龋齿不平等问题的国际合作研究提供科学框架。
遵循公认的指南。通过电子检索确定研究,并由两名评审员根据关键词、标题和摘要进行评审,以评估是否符合纳入标准。获取所有文章的副本,并根据研究设计评估其质量。
通过电子检索识别出1029篇论文,260篇符合初步纳入标准。在获取这些论文的全文后,排除了183篇。在纳入的77项研究中,43项为横断面研究,19项为队列研究,8项为病例对照研究,7项为干预性研究。很少有研究获得最高质量评分。106个危险因素与龋齿的患病率或发病率显著相关。
缺乏使用最佳研究设计(即纵向研究)的高质量研究。证据表明,如果儿童在幼年时感染变形链球菌,最有可能患龋齿,尽管这可能会部分被其他因素(如良好的口腔卫生和非致龋性饮食)所抵消。饮食和口腔卫生可能相互作用,因此,如果通过保持良好的菌斑控制养成“良好”习惯,同时通过食用致龋性饮食养成“不良”习惯之间达到平衡,龋齿的发展可能会得到控制。