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阴茎癌治疗的当前趋势——综述

Current trends in the management of carcinoma penis--a review.

作者信息

Singh Iqbal, Khaitan A

机构信息

Department of Surgery, University College of Medical Sciences (University of Delhi) & Guru Tegh Bahadur Hospital, Delhi-95, India.

出版信息

Int Urol Nephrol. 2003;35(2):215-25. doi: 10.1023/b:urol.0000020339.92722.33.

Abstract

UNLABELLED

AIMS AND INTRODUCTION: To review the current literature, recent advances and recent trends in the management of squamous cell carcinoma of the penis so as to have a broad overview of penile cancer and its current management. The review was considered keeping in mind that squamous penile carcinoma is an infrequently encountered malignancy and that the etiology is still unclear though certain predisposing conditions are known to exist and also that controversy still exists as to the appropriate management of inguinal adenopathy. We also reviewed the etiological factors, clinical presentation, diagnosis, staging, prognostic factors in addition to management and prophylaxis.

METHODS

A literature search was carried out from Pubmed for indexed articles published over the last 50 years using the key words 'Management penile carcinoma', 'Squamous cell carcinoma penis' and 'inguinal lymphadenectomy'.

RESULTS

The search yielded over 1500 indexed published articles and reports. Important major reports and studies were reviewed, screened and tracked for recent changes and trends in the management of penile cancer. These were analyzed, tabulated and discussed.

CONCLUSIONS

Newer approaches to the management of penile cancer include use of laser, photodynamic therapy, neoadjuvant therapy and sentinel node mapping by lympho-gamma-scintigraphy. The current approach towards managing inguinal adenopathy shows an increasing trend towards the use of these newer modalities as well as the use of certain modifications in lympadenectomy such as (the use of ligasure, modified dissection, saphenous vein sparing and lymphoscintigraphy, etc.) thereby making the procedure considerably less morbid than before.

摘要

未标注

目的与引言:回顾阴茎鳞状细胞癌治疗的当前文献、最新进展和最新趋势,以便对阴茎癌及其当前治疗有一个全面的了解。进行这项综述时考虑到阴茎鳞状细胞癌是一种罕见的恶性肿瘤,尽管已知某些诱发因素,但病因仍不清楚,而且对于腹股沟淋巴结病的适当治疗仍存在争议。除了治疗和预防外,我们还回顾了病因、临床表现、诊断、分期和预后因素。

方法

使用关键词“阴茎癌治疗”“阴茎鳞状细胞癌”和“腹股沟淋巴结切除术”在PubMed上搜索过去50年发表的索引文章。

结果

搜索产生了1500多篇索引发表的文章和报告。对重要的主要报告和研究进行了回顾、筛选,并追踪阴茎癌治疗的最新变化和趋势。对这些进行了分析、列表和讨论。

结论

阴茎癌治疗的新方法包括使用激光、光动力疗法、新辅助治疗以及通过淋巴γ闪烁显像进行前哨淋巴结定位。目前处理腹股沟淋巴结病的方法显示出越来越倾向于使用这些新方法以及在淋巴结切除术中进行某些改进,如(使用结扎速、改良解剖、保留大隐静脉和淋巴闪烁显像等),从而使该手术的发病率比以前大大降低。

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