Kvarstein Bernt, Fosså Sophie D, Harvei Sverre
Urologisk seksjon Akershus universitetssykehus 1474 Nordbyhagen.
Tidsskr Nor Laegeforen. 2002 May 10;122(12):1194-7.
Penile cancer is a rare malignancy in Norway with about 40 new cases each year.
An overview on diagnosis and treatment of penile cancer is given and the guidelines from the European Association of Urology are presented.
Phimosis and poor genital hygiene are pre-disposing conditions for penile cancer. Condylomata acuminatum and leukoplakia should be regarded as premalignant lesions. The superficial form of penile cancer should be treated by laser, surgery or radiotherapy. When the cancer infiltrates into corpus cavernosum or corpus spongiosum, or the tumour displays a poorly differentiated histology, a partial or total amputation of the penis has to be performed. Inguinal lymphadenectomy is recommended in patients presenting with a tumour > or = pT2 or if the histology reveals a moderately or poorly differentiated cancer. Five-year survival rate is about 80% for patients with localised tumour, and about 50% in patients with regional lymph node metastasis.
We recommend that the treatment of penile cancer is performed in the regional hospitals.
阴茎癌在挪威是一种罕见的恶性肿瘤,每年约有40例新发病例。
本文给出了阴茎癌诊断和治疗的概述,并介绍了欧洲泌尿外科学会的指南。
包茎和生殖器卫生状况差是阴茎癌的诱发因素。尖锐湿疣和白斑应被视为癌前病变。阴茎癌的浅表型应采用激光、手术或放射治疗。当癌症浸润到海绵体或海绵体时,或肿瘤显示出低分化组织学特征时,必须进行阴茎部分或全部切除。对于肿瘤≥pT2期或组织学显示为中分化或低分化癌的患者,建议进行腹股沟淋巴结清扫术。局限性肿瘤患者的五年生存率约为80%,区域淋巴结转移患者的五年生存率约为50%。
我们建议在地区医院进行阴茎癌的治疗。