Dancini José Luiz, Pomerantzeff Pablo Maria Alberto, Spina Guilherme Sobreira, Pardi Mírian Magalhães, Giorgi Maria Clementina Pinto, Sampaio Roney Orismar, Grinberg Max, Oliveira Sérgio Almeida de
Instituto do Coração, Hospital das Clínicas, FM, USP.
Arq Bras Cardiol. 2004 Mar;82(3):235-42. doi: 10.1590/s0066-782x2004000300004. Epub 2004 Apr 5.
To compare, from the clinical and laboratory points of view, 3 groups of patients undergoing surgical treatment for isolated chronic mitral insufficiency. One group underwent valvuloplasty, and the other 2 groups underwent mitral valve replacement with different techniques for chordal preservation.
Twenty-eight patients with a mean age of 54.1 years, no coronary or multivalvular disease, and no reoperation, underwent surgery as follows: 9 underwent valvuloplasty; 10 underwent mitral valve replacement with chordal preservation in both leaflets; and 9 underwent mitral valve replacement with chordal preservation only in the posterior leaflet. Clinical, Doppler echocardiographic, and radionuclide ventriculographic assessments were performed until the 6th month of follow-up.
At the end, 88.8% of the patients were in functional class I. One died due to intracranial hemorrhage during anticoagulant treatment. The left ventricular diastolic diameter (P<0.0001) and end-diastolic volume (P<0.0001) decreased in the 3 groups. Only the patients undergoing valvuloplasty had a decrease in systolic diameter (P=0.0003) and in end-systolic volume (P=0.0040), with no change in the ejection fraction (P=0.5586). The patients undergoing mitral valve replacement had a similar drop in ejection fraction (P=0.0001 and P=0.0296).
The 3 surgical techniques used provided clinical improvement. Patients undergoing valvuloplasty had better preservation of ventricular function. No significant difference was observed in cardiac performance between the 2 groups undergoing mitral valve replacement with chordal preservation within a 6-month follow-up.
从临床和实验室角度比较3组接受单纯慢性二尖瓣关闭不全手术治疗的患者。一组接受瓣膜成形术,另外两组采用不同的腱索保留技术进行二尖瓣置换术。
28例平均年龄54.1岁、无冠状动脉疾病或多瓣膜疾病且未接受再次手术的患者接受了如下手术:9例行瓣膜成形术;10例行双叶腱索保留二尖瓣置换术;9例行仅后叶腱索保留二尖瓣置换术。在随访的第6个月前进行临床、多普勒超声心动图和放射性核素心室造影评估。
最后,88.8%的患者心功能分级为I级。1例在抗凝治疗期间因颅内出血死亡。3组患者的左心室舒张直径(P<0.0001)和舒张末期容积(P<0.0001)均减小。仅接受瓣膜成形术的患者收缩直径(P=0.0