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[美罗培南在儿童中的临床评估]

[Clinical evaluation of meropenem in children].

作者信息

Fukushima N, Ishikawa A, Takase A, Wagatsuma Y

机构信息

Department of Pediatrics, Sapporo City General Hospital.

出版信息

Jpn J Antibiot. 1992 Jun;45(6):734-7.

PMID:1507404
Abstract

Meropenem (MEPM) was evaluated for its efficacy and safety. The following results were obtained. MEPM was given to 12 patients with infections: 5 with pneumonia, 1 with bacterial meningitis, 2 with pharyngitis, 4 with skin and soft tissue infections. Therapeutic responses were "excellent" in 5, "good" in 4 and "fair" in 3, with an efficacy rate of 75%. Adverse reactions were not noted. No abnormalities were shown in laboratory data. It has been concluded that MEPM is a useful drug for the treatment of bacterial infections in children.

摘要

对美罗培南(MEPM)的疗效和安全性进行了评估。得到了以下结果。对12例感染患者给予了MEPM:5例患有肺炎,1例患有细菌性脑膜炎,2例患有咽炎,4例患有皮肤和软组织感染。治疗反应为“优秀”的有5例,“良好”的有4例,“中等”的有3例,有效率为75%。未观察到不良反应。实验室数据未显示异常。得出的结论是,MEPM是治疗儿童细菌感染的一种有用药物。

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