Soeda K, Kanno H, Isono K
Second Department of Surgery, Chiba University School of Medicine.
Nihon Rinsho. 1992 May;50(5):1093-8.
MRSA strains were first isolated in 1981 and have increased markedly from 1985 in our surgical ward. One hundred and ninety four strains of MRSA were isolated and 81 cases developed critical infections which were associated with enterocolitis, pneumonia and sepsis. There were many cases in esophageal cancer patients. Bacteriological features of the MRSA strains clearly changed in 1985 from IV to II coagulase type, accompanied with high resistance for antibiotics. Our management against nosocomial infection for MRSA started from April 1988. The number of MRSA cases decreased in 1989, increased in 1990 and decreased again in 1991. We are confident that our management is effective and we will take further efforts to choose the most adequate antibiotics after surgery in our surgical ward.
耐甲氧西林金黄色葡萄球菌（MRSA）菌株于1981年首次分离出来，自1985年起在我们的外科病房中显著增加。共分离出194株MRSA菌株，81例患者发生了严重感染，这些感染与小肠结肠炎、肺炎和败血症有关。食管癌患者中有很多病例。1985年，MRSA菌株的细菌学特征从IV型明显转变为II型凝固酶型，同时对多种抗生素具有高耐药性。我们针对MRSA医院感染的管理措施于1988年4月开始实施。MRSA病例数在1989年有所下降，1990年有所增加，1991年再次下降。我们相信我们的管理措施是有效的，并且我们将进一步努力在外科病房中选择术后最适宜的抗生素。
