López-Campos José Luis, Rodríguez-Becerra Eulogio
Medical-Surgical Unit of Respiratory Diseases, 'Virgen del Rocío' University Hospital, Seville, Spain.
Eur J Epidemiol. 2004;19(2):155-61. doi: 10.1023/b:ejep.0000017660.18541.83.
This study aims to describe the distribution of interstitial lung diseases (ILD) in the South of Spain.
A prospective multicentre population-based registry was established in nine provinces in the south of Spain with a population of 6,848,243 during a 3-year period (1998-2000). The number of participant physicians was 36 among 29 public hospitals. The number of diagnoses recorded was 66, divided in eight categories and coded according to ICD-9. A consensus document was elaborated for the classification of diseases and their diagnostic criteria. The number of cases declared was analysed each 3 months and communicated to each one of the participants.
There were 744 cases of them registered with an annual incidence of 3.62 cases/ 100,000. 40.1% of diagnoses were biopsy confirmed. Men had a slightly higher incidence (4.18 cases/ 100,000/year) than women (3.07 cases/100,000/year). The most frequent diseases found were: idiopathic interstitial pneumonias (38.58%), ILD associated to systemic diseases (20.97%), and Sarcoidosis (11.69%). According to province distribution, most of the cases were grouped in an area between the provinces of Seville and Cordoba, which comprised more than 50% of cases.
The study of the incidence of ILD depicts an intermediate situation from previous studies on the incidence and distribution of this group of diseases.
本研究旨在描述西班牙南部间质性肺疾病（ILD）的分布情况。
在西班牙南部九个省份建立了一个前瞻性多中心基于人群的登记处，在三年期间（1998 - 2000年）覆盖人口6,848,243。29家公立医院中有36名参与医生。记录的诊断病例数为66例，分为八类并根据国际疾病分类第九版（ICD - 9）编码。制定了一份关于疾病分类及其诊断标准的共识文件。每三个月分析申报的病例数并传达给每位参与者。
共登记了744例病例，年发病率为3.62例/10万。40.1%的诊断经活检证实。男性发病率（4.18例/10万/年）略高于女性（3.07例/10万/年）。最常见的疾病为：特发性间质性肺炎（38.58%）、与全身性疾病相关的ILD（20.97%）和结节病（11.69%）。根据省份分布，大多数病例集中在塞维利亚省和科尔多瓦省之间的一个区域，该区域病例占比超过50%。
对ILD发病率的研究呈现出与以往关于这组疾病发病率和分布的研究相比处于中间水平的情况。
