Herr Harry, Lee Cheryl, Chang Sam, Lerner Seth
Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
J Urol. 2004 May;171(5):1823-8; discussion 1827-8. doi: 10.1097/01.ju.0000120289.78049.0e.
We propose standards for radical cystectomy and pelvic lymph node dissection in the surgical treatment of patients with invasive bladder cancer.
We compiled the consecutive cystectomy experience of 16 experienced surgeons during the last 3 years (2000 to 2002) from 4 institutions. We evaluated patient, tumor and surgical variables of margin status, extent of pelvic node dissection, number of nodes examined and surgeon volume associated with bladder cancer outcomes.
A total of 1,091 cystectomy cases were evaluated. Surgical margins and number of nodes retrieved correlated with patient age, prior treatments, pathological tumor stage and extent of node dissection, but not surgeon volume.
Standards for radical cystectomy can be established and achieved by experienced surgeons operating on patients presenting with diverse clinical situations.
我们提出了根治性膀胱切除术及盆腔淋巴结清扫术治疗浸润性膀胱癌患者的手术标准。
我们汇总了4家机构16位经验丰富的外科医生在过去3年(2000年至2002年)连续进行膀胱切除术的经验。我们评估了患者、肿瘤及手术变量,包括切缘状态、盆腔淋巴结清扫范围、检查的淋巴结数量以及与膀胱癌治疗结果相关的外科医生手术量。
共评估了1091例膀胱切除术病例。手术切缘和切除的淋巴结数量与患者年龄、既往治疗、病理肿瘤分期及淋巴结清扫范围相关,但与外科医生手术量无关。
经验丰富的外科医生在面对不同临床情况的患者进行手术时,可以制定并达到根治性膀胱切除术的标准。