McLean Kathryn R
Women and Infants' Hospital, 101 Dudley Street, Providence, RI 02905, USA.
Neonatal Netw. 2004 Mar-Apr;23(2):7-14. doi: 10.1891/0730-0832.23.2.7.
Osteogenesis imperfecta (OI) is a rare congenital disorder of collagen production that results in brittle bones and affects other body systems containing collagen. This article reviews the current body of knowledge about OI and the management of infants with the disorder. Relieving pain, reducing the incidence of new fractures, establishing adequate follow-up, and connecting parents with community resources are the goals of management during the neonatal period. A case study illustrates management and the discharge process.
成骨不全症（OI）是一种罕见的先天性胶原蛋白生成障碍疾病，会导致骨骼脆弱，并影响其他含有胶原蛋白的身体系统。本文综述了目前关于成骨不全症的知识体系以及对患有该疾病婴儿的管理。缓解疼痛、降低新骨折的发生率、建立充分的随访以及让家长与社区资源建立联系是新生儿期管理的目标。一个案例研究说明了管理和出院过程。
