Starostenko I N, Preĭgel' I A
Klin Med (Mosk). 1992 Feb;70(2):81-4.
The authors investigated a prognostic value (with respect to the complications) of certain laboratory parameters used in the examination of the gastric juice in patients with duodenal ulcer (DU) as well as the prognostic value of certain anamnestic data. A total of 100 patients with DU who had been followed up for 5-6 years were under study. The results obtained demonstrated the most informative values for the DU-related complications turned to be the parameters of the performance of the defense mechanisms of the gastroduodenal area (the contents of mucous proteins, the coefficient of the gastric juice defense), the levels of gastric secretion and acidification (the quantity of the juice, the per hour discharge of hydrochloric acid) as well as the ratio between the coefficient of the defense and the coefficient of the pepsin aggression that reflected the ratio between the aggressive and defensive factors of the gastric juice. Defined discriminant functions permitted the prognostication of complications appearance correct within 80-90%.
作者研究了十二指肠溃疡（DU）患者胃液检查中某些实验室参数对并发症的预后价值以及某些既往史数据的预后价值。共有100例DU患者接受了5至6年的随访研究。所获结果表明，对DU相关并发症最具信息价值的是胃十二指肠区域防御机制的指标（黏液蛋白含量、胃液防御系数）、胃分泌和酸化水平（胃液量、每小时盐酸排出量）以及反映胃液攻击与防御因素比例的防御系数与胃蛋白酶攻击系数之比。所确定的判别函数对并发症出现的预测准确率为80%至90%。
