Sinitsina T M, Klimenkova S F, Korosteleva N Iu, Bolodon S A
Klin Med (Mosk). 1992 Mar-Apr;70(3-4):46-8.
Forty-eight patients with chronic renal insufficiency (CRI) receiving hemodialysis (24 males and 24 females) aged 17-62 underwent bicycle exercise to measure diffuse capacity of the lungs (DCL) before and after the test. DCL components (membraneous and blood volume in pulmonary capillaries, Vc) were defined in 33 out of 48 patients. DCL appeared to reduce significantly (up to 65 +/- 2%) at the expense of Vc fall to 51 +/- 4.5% and membraneous component decline, to 65 +/- 4%. DCL depended on severity of anemia, hemodialysis efficiency, electrolyte metabolism activity and CRI gravity. Performance status in CRI patients is limited by DCL value responsible for maximal oxygen consumption under exercise being independent on duration and type of hemodialysis.
48例接受血液透析的慢性肾功能不全（CRI）患者（男性24例，女性24例），年龄17 - 62岁，在测试前后进行自行车运动以测量肺弥散容量（DCL）。48例患者中有33例明确了DCL的组成部分（肺毛细血管膜和血容量，Vc）。DCL似乎显著降低（高达65±2%），这是以Vc降至51±4.5%和膜性成分下降至65±4%为代价的。DCL取决于贫血的严重程度、血液透析效率、电解质代谢活性和CRI的严重程度。CRI患者的功能状态受DCL值限制，DCL值决定运动时的最大耗氧量，且与血液透析的持续时间和类型无关。
