von Hattingberg H M
Zentrum für Kinderheilkunde, Giessen, FRG.
Methods Find Exp Clin Pharmacol. 1992 May;14(4):289-95.
UNICEF, the United Nations International Children Emergency Funds, has staged an enormous program to improve children's health conditions in the developing countries. One extremely fruitful field of engagement was, and still is, the treatment of dehydration. Oral rehydration therapy (ORT) has reluctantly been accepted in the industrialized countries. From clinical observations, we have gained a new understanding of known pathophysiological principles. Dehydration most often is a result of diarrhea, and therefore oral rehydration therapy is mostly referred to in the context of infections of the digestive system. We discuss additional causes of dehydration and its immediate and secondary consequences. We demonstrate not only that, but why and how, a very simple, inexpensive regimen is beneficial and effective in the treatment of dehydration. Without consideration of sodium deficit, understanding will fail, and treatment will remain ineffective.
联合国儿童基金会，即联合国国际儿童紧急基金，开展了一项庞大的计划来改善发展中国家儿童的健康状况。一个极其富有成效的参与领域过去是、现在仍然是脱水治疗。口服补液疗法（ORT）在工业化国家一直未得到广泛认可。通过临床观察，我们对已知的病理生理原则有了新的认识。脱水最常见的原因是腹泻，因此口服补液疗法大多在消化系统感染的背景下被提及。我们讨论了脱水的其他原因及其直接和间接后果。我们不仅证明了一种非常简单、廉价的治疗方案在治疗脱水方面是有益且有效的，还阐述了其原因和方式。如果不考虑钠缺乏，就无法理解，治疗也将仍然无效。
