Thakur Mamta, Agarwal Alok, Thakur Abhilash, Khadikar Padmakar V
Department of Chemistry, Soft Vision College of Biotechnology and Science, 7, Green pank Colony, Indore 452001, India.
Bioorg Med Chem. 2004 May 1;12(9):2287-93. doi: 10.1016/j.bmc.2004.02.010.
The phenolic activity (log 1/C) of a large series of phenols against L1210 leukaemia cells was modelled using physicochemical parameters other than conventional electronic and steric parameters. Attempts have also been made to examine need or otherwise of the hydrophobic parameter, log P, in such studies. The results have shown that contribution of log P in modelling log 1/C is favourable.
