McDonald L Clifford, Lauderdale Tsai-Ling, Shiau Yih-Ru, Chen Pei-Chen, Lai Jui-Fen, Wang Hui-Ying, Ho Monto
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Int J Antimicrob Agents. 2004 Apr;23(4):362-70. doi: 10.1016/j.ijantimicag.2003.09.021.
In the Taiwan Surveillance of Antimicrobial Resistance programme, isolates were collected from 21 hospitals over a 3-month period in 2000 (TSAR II) and rates of resistance in Gram-positive pathogens were determined. Resistance rates were high including oxacillin resistance in Staphylococcus aureus (60%) and coagulase-negative staphylococci (80%), high-level gentamicin resistance (HLGR) in Enterococcus faecalis (60%) and penicillin non-susceptibility in Streptococcus pneumoniae (69%). Oxacillin resistance had increased from 1998 (TSAR I) and may be spreading into outpatient settings. In contrast, less than 2% enterococci were vancomycin-resistant. No linezolid resistance was found in either staphylococci or enterococci.
在台湾抗菌药物耐药性监测计划中，于2000年的3个月期间从21家医院收集了分离株（TSAR II），并测定了革兰氏阳性病原体的耐药率。耐药率很高，包括金黄色葡萄球菌对苯唑西林的耐药率（60%）和凝固酶阴性葡萄球菌（80%）、粪肠球菌对高水平庆大霉素的耐药率（60%）以及肺炎链球菌对青霉素的不敏感率（69%）。苯唑西林耐药率自1998年（TSAR I）以来有所上升，且可能正在蔓延至门诊环境。相比之下，不到2%的肠球菌对万古霉素耐药。在葡萄球菌或肠球菌中均未发现对利奈唑胺耐药的情况。
