1,5-二芳基-5-[¹⁴C]-1,2,3-三唑的碳-14类似物的合成
Synthesis of carbon-14 analogue of 1,5 diaryl-5-[14C]-1,2,3-triazoles.
作者信息
Matloubi Hojatollah, Shafiee Abbas, Saemian Nader, Shirvani Gholamhossein, Daha Fariba Johari
机构信息
Nuclear Research Center/AEOI, Chemical Division P.O. Box 11365-3486, Tehran, Iran.
出版信息
Appl Radiat Isot. 2004 May;60(5):665-8. doi: 10.1016/j.apradiso.2003.12.003.
Abstract
Two 1,2,3-triazole anticonvulsants, 1-(4-methylsulfone-phenyl)-5-(4-methyl-phenyl)-1,2,3-triazole and 1-(4-methylsulfone-phenyl)-5-phenyl-1,2,3-triazole, both labeled with carbon-14 in the 5-position were prepared from para-tolunitrile-[cyano-14C] and benzonitrile-[cyano-14C], respectively.
摘要
两种1,2,3 - 三唑类抗惊厥药，1-(4 - 甲基砜基苯基)-5-(4 - 甲基苯基)-1,2,3 - 三唑和1-(4 - 甲基砜基苯基)-5 - 苯基-1,2,3 - 三唑，二者均在5位用碳 - 14标记，分别由对甲苯腈-[氰基 - 14C]和苄腈-[氰基 - 14C]制备而成。
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