Burle Borís, Vidal Franck, Bonnet Michel
Centre National de la Recherche Scientifique and Université de Provence, Laboratoire de Neurobiologie de la Cognition, Marseille, France.
Neurosci Lett. 2004 Apr 22;360(1-2):77-80. doi: 10.1016/j.neulet.2004.02.034.
The nogo potentials (N2/P3) were studied in a precuing auditory reaction time task in human subjects who had to either perform a button-press response (Press condition) or imagine they were performing it (Imagine condition). In the full precue condition (the subjects knew in advance which response they had to perform/imagine), in 25% of the trials, a nogo signal instructed the subject not to perform or not to imagine the prepared action. Clear N2/P3 components were obtained on nogo trials on the Press trials, but also on the Imagine ones: the N2 was of similar amplitude in both conditions, whereas the P3 was of smaller amplitude in the Imagine condition. The presence of nogo potential in motor imagery is discussed in terms of the functional significance of the N2/P3 complex.
在一项预提示听觉反应时任务中，对人类受试者的失匹配负波（N2/P3）进行了研究。这些受试者要么执行按键反应（按压条件），要么想象自己在执行该反应（想象条件）。在完全预提示条件下（受试者提前知道他们必须执行/想象哪种反应），在25%的试验中，一个失匹配信号指示受试者不要执行或不要想象准备好的动作。在按压试验的失匹配试验中，以及在想象试验中，都获得了清晰的N2/P3成分：在两种条件下，N2的振幅相似，而在想象条件下，P3的振幅较小。从N2/P3复合体的功能意义方面讨论了运动想象中失匹配负波的存在。
