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钬激光治疗儿童下鼻甲肥大的临床与组织学研究

Inferior turbinate reduction in children using Holmium YAG laser-a clinical and histological study.

作者信息

Rejali S D, Upile T, McLellan D, Bingham B J G

机构信息

Department of Otolaryngology, Southern General Hospital, Glasgow, United Kingdom.

出版信息

Lasers Surg Med. 2004;34(4):310-4. doi: 10.1002/lsm.20037.

Abstract

BACKGROUND AND OBJECTIVES

To compare the efficacy and safety of inferior turbinate reduction in children using Holmium:YAG (Ho:Yag) laser and diathermy. Histological effects of these treatments on turbinate tissue are also studied.

STUDY DESIGN/MATERIALS AND METHODS: A retrospective review and structured telephone interview of paediatric cases treated with Ho:Yag laser and diathermy to inferior turbinates. The complications, morbidity and efficacy were quantified. Histological sections of inferior turbinates treated with diathermy (surface and submucosal) and laser were compared.

RESULTS

Efficacy in the laser (n = 8) and diathermy group (n = 11) was similar. The complication/morbidity score was lower in the laser group, 1.92 versus 3.48, (P = 0.04, CI: 0.01, 2). Long-term benefit was 50 and 36% in the laser and diathermy group respectively. Histology showed very limited tissue damage in all methods of treatment.

CONCLUSIONS

Ho:Yag laser treatment is equally efficacious, but causes less complications and morbidity compared to surface diathermy. Both treatment methods have poor long-term efficacy, which may be related to limited tissue damage.

摘要

背景与目的

比较使用钬激光(Ho:Yag)和透热法对儿童下鼻甲进行缩小治疗的疗效和安全性。此外,还研究了这些治疗方法对鼻甲组织的组织学影响。

研究设计/材料与方法:对接受Ho:Yag激光和透热法治疗下鼻甲的儿科病例进行回顾性研究和结构化电话访谈。对并发症、发病率和疗效进行量化。比较透热法(表面和黏膜下)和激光治疗的下鼻甲组织学切片。

结果

激光组(n = 8)和透热法组(n = 11)的疗效相似。激光组的并发症/发病率评分较低,分别为1.92和3.48,(P = 0.04,CI:0.01,2)。激光组和透热法组的长期获益分别为50%和36%。组织学显示,所有治疗方法造成的组织损伤都非常有限。

结论

Ho:Yag激光治疗同样有效,但与表面透热法相比,并发症和发病率更低。两种治疗方法的长期疗效都较差,这可能与有限的组织损伤有关。

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