Cubadda Francesco
National Center for Food Quality and Risk Assessment, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
J AOAC Int. 2004 Jan-Feb;87(1):173-204.
Inductively coupled plasma-mass spectrometry (ICP-MS) has definitely emerged as a powerful technique for total element determination and as a sensitive and selective detector in hyphenated methods for speciation analyses of elements in foods. In this review, the analytical challenges of elemental analysis of food and agricultural matrixes are discussed and several applications are examined. Selected examples illustrate the analytical approaches being used so far to address specific issues in various areas of food and nutrition research. The applications discussed include studies on dietary intake, element metabolism in man, transfer of elements through the food chain, effects of food processing and domestic preparation, and authenticity and origin assessment. The use of ICP-MS in the field of analytical quality assurance, food control, evaluation of food contact materials, and radionuclide contamination is also examined. Finally, the hyphenated techniques with ICP-MS detection used for elemental speciation in food are reviewed, and an overview of the main applications currently in the literature is presented. Throughout, recent trends and analytical developments likely to have a major impact on food-related areas are highlighted.
电感耦合等离子体质谱法（ICP-MS）无疑已成为一种用于测定元素总量的强大技术，并且在食品中元素形态分析的联用方法中作为一种灵敏且选择性的检测器。在本综述中，讨论了食品和农业基质元素分析的分析挑战，并考察了若干应用。所选示例说明了迄今为止用于解决食品和营养研究各个领域特定问题的分析方法。所讨论的应用包括膳食摄入量研究、人体元素代谢、元素在食物链中的转移、食品加工和家庭制备的影响以及真实性和产地评估。还考察了ICP-MS在分析质量保证、食品控制、食品接触材料评估和放射性核素污染领域的应用。最后，综述了用于食品中元素形态分析的带有ICP-MS检测的联用技术，并概述了当前文献中的主要应用。贯穿全文，突出了可能对食品相关领域产生重大影响的最新趋势和分析进展。
