Dustin Michael
New York University School of Medicine, Skirball Institute of Molecular Medicine, Department of Pathology, Program in Molecular Pathogenesis, 540 First Avenue, New York, NY 10016, USA.
Immunity. 2004 Apr;20(4):361-2. doi: 10.1016/s1074-7613(04)00083-4.
Siegelman and colleagues demonstrate unexpected synergism of CD44 and VLA-4 during lymphocyte extravasation. This is the first time that molecules mediating rolling and firm adhesion have been shown to associate biochemically leading to direct functional cooperation.
