Nakao Akimasa, Takeda Shin, Sakai Mitsuru, Kaneko Tetsuya, Inoue Soichiro, Sugimoto Hiroyuki, Kanazumi Naohito
Department of Surgery II, Nagoya University Hospital, Nagoyashi, Japan.
Pancreas. 2004 Apr;28(3):289-92. doi: 10.1097/00006676-200404000-00014.
This clinical study was carried out to clarify the indications for extended radical resection for pancreatic carcinoma.
From July 1981 to September 2003, 250 of 391 (63.9%) patients with pancreatic carcinoma underwent tumor resection in our department. Portal vein resection was performed in 171 of these 250 (68.4%) resected cases. The postoperative survival rate was studied using the operative and histologic findings.
Most of the patients who survived for 2 or 3 years were in the carcinoma-free surgical margins group.
The most important indication for an extended radical resection combined with portal vein resection for pancreatic cancer is the ability to obtain surgical cancer-free margins. There is no indication for an extended resection in patients in whom the surgical margins will become cancer positive if such an operation is employed.
开展本临床研究以明确胰腺癌扩大根治性切除术的适应证。
1981年7月至2003年9月，我科391例胰腺癌患者中有250例（63.9%）接受了肿瘤切除术。这250例接受切除术的患者中，171例（68.4%）进行了门静脉切除术。利用手术和组织学检查结果研究术后生存率。
存活2年或3年的患者大多处于手术切缘无癌组。
胰腺癌扩大根治性切除术联合门静脉切除术的最重要适应证是能够获得无癌手术切缘。对于采用此类手术会导致手术切缘癌阳性的患者，没有扩大切除术的适应证。
