Bonebrake Robert G, Fleming Alfred D, Carignan Eva M, Hoover Diana K
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Creighton University Medical Center/Bergan Mercy Medical Center, Omaha, Nebraska 68131, USA.
Am J Perinatol. 2004 Apr;21(3):153-5. doi: 10.1055/s-2004-823774.
Preeclampsia is a common complication of pregnancy and often manifests in severe cases with neurological symptoms. We present the first documented case of preeclampsia associated with third nerve palsy. A 19-year-old primigravida presented at 31 2/7 weeks' gestation with preeclampsia. In addition to classic preeclampsia symptoms, the patient had atypical visual disturbances. Exhaustive neurological and ophthalmological examinations revealed a third nerve palsy with no etiology other than preeclampsia. Deteriorating renal function necessitated preterm delivery. She ultimately underwent a cesarean section. Two months postpartum, the patient has shown complete spontaneous resolution of third nerve palsy. In this case of severe preeclampsia manifested by third nerve palsy, we hypothesize that the mechanism is attributed to vasospasm of the vessels supplying the oculomotor nerve.
子痫前期是妊娠常见并发症,重症常伴有神经症状。我们报告首例有记录的子痫前期合并动眼神经麻痹病例。一名19岁初产妇在妊娠31 2/7周时因子痫前期就诊。除典型子痫前期症状外,患者有非典型视觉障碍。全面的神经和眼科检查显示为动眼神经麻痹,病因仅为子痫前期。肾功能恶化需要早产。她最终接受了剖宫产。产后两个月,患者动眼神经麻痹完全自发缓解。在这例以动眼神经麻痹为表现的重度子痫前期病例中,我们推测其机制是供应动眼神经的血管发生血管痉挛。