Antoniades Demetrios, Harrison John D, Epivatianos Apostolos, Papanayotou Panayotis
Department of Oral Medicine and Oral Pathology, Dental School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
J Oral Maxillofac Surg. 2004 Apr;62(4):431-4. doi: 10.1016/j.joms.2003.07.007.
We sought to describe the treatment of chronic sialadenitis by intraductal penicillin or saline.
The study group consisted of 32 males and 23 females with chronic submandibular sialadenitis aged 12 to 65 years and 16 males and 11 females with chronic parotitis aged 8 to 65 years who were treated by intraductal instillation of penicillin or saline.
In the patients with submandibular sialadenitis, 44 patients treated with penicillin and 11 treated with saline became symptom free; symptoms recurred in 3 treated with penicillin, of whom 2 became symptom free after further instillations and 1 after removal of a sialolith at the ductal orifice; and follow-up of 22 patients verified that 18 treated with penicillin and 4 with saline had been symptom free for 1 to 15 years and 1 to 3 years, respectively. In the patients with parotitis, 18 patients treated with penicillin, 8 treated with saline, and 1 treated with both became symptom free; symptoms recurred in 1 treated with penicillin and 1 with saline, both of whom became symptom free after further instillations; and follow-up of 15 patients verified that 11 treated with penicillin, 3 with saline, and 1 with both had been symptom free for 1 to 14 years, 2 to 12 years, and 3 years, respectively.
The intraductal instillation of penicillin or saline is a simple and surprisingly successful technique for the treatment of chronic sialadenitis.
我们试图描述通过导管内注射青霉素或生理盐水治疗慢性涎腺炎的情况。
研究组包括32例男性和23例女性慢性下颌下涎腺炎患者,年龄在12至65岁之间,以及16例男性和11例女性慢性腮腺炎患者,年龄在8至65岁之间,他们接受了导管内注射青霉素或生理盐水的治疗。
在下颌下涎腺炎患者中,44例接受青霉素治疗和11例接受生理盐水治疗的患者症状消失;3例接受青霉素治疗的患者症状复发,其中2例在进一步注射后症状消失,1例在导管口取出涎石后症状消失;对22例患者的随访证实,18例接受青霉素治疗和4例接受生理盐水治疗的患者分别在1至15年和1至3年内无症状。在腮腺炎患者中,18例接受青霉素治疗、8例接受生理盐水治疗和1例接受两种治疗的患者症状消失;1例接受青霉素治疗和1例接受生理盐水治疗的患者症状复发,两人在进一步注射后症状消失;对15例患者的随访证实,11例接受青霉素治疗、3例接受生理盐水治疗和1例接受两种治疗的患者分别在1至14年、2至12年和3年内无症状。
导管内注射青霉素或生理盐水是一种治疗慢性涎腺炎的简单且出人意料地成功的技术。