Delhaas E M, Verhagen J
Department of Anaesthesiology, Sophia Hospital, Zwolle, The Netherlands.
Paraplegia. 1992 Jul;30(7):527-8. doi: 10.1038/sc.1992.110.
A report on pregnancy in a quadriplegic patient treated with a high dose of 1000 mcg/24 h continuous intrathecal baclofen infusion using an implanted drug delivery system (Synchromed, Medtronic, USA). Spasticity could be managed up to the 35th week of gestation. However, uterine contractions evoke enormous spastic symptoms which we, even with maximum values of the spasticity scales, could not classify. The recurrence of spasticity was associated with autonomic dysregulation. With continuous epidurally infused bupivacaine (11.25 mg/h) adequate relaxation could be reached and gestation was terminated by a primary caesarean section. A healthy girl was born (2040 g, Apgar 9 and 10).
一份关于一名四肢瘫痪患者怀孕情况的报告,该患者使用植入式药物输送系统(美国美敦力公司的Synchromed)以1000微克/24小时的高剂量持续鞘内注射巴氯芬进行治疗。痉挛在妊娠35周前都能得到控制。然而,子宫收缩引发了巨大的痉挛症状,即使在痉挛量表的最大值情况下,我们也无法对其进行分类。痉挛的复发与自主神经调节异常有关。通过持续硬膜外输注布比卡因(11.25毫克/小时),可以达到充分的松弛效果,并通过初次剖宫产终止妊娠。一名健康女婴出生(体重2040克,阿氏评分9分和10分)。