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患有骨髓纤维化的婴儿同胞肾脏中的髓外造血。

Extramedullary hematopoiesis in the kidneys in infant siblings with myelofibrosis.

作者信息

Fernbach S K, Feinstein K A

机构信息

Children's Memorial Hospital, Chicago, Illinois.

出版信息

Pediatr Radiol. 1992;22(3):211-2. doi: 10.1007/BF02012499.

DOI:10.1007/BF02012499
PMID:1508592
Abstract

Extramedullary hematopoiesis (EMH) is known to occur in clinical settings associated with severe anemia. Because very young children with anemia can usually recruit the still large compartment of red marrow, EMH is more frequently seen in adults. We have observed two young girls, who were unable to produce sufficient blood products in their marrow and instead developed EMH, one with documented and rarely reported renal involvement. They are described below.

摘要

已知髓外造血(EMH)发生在与严重贫血相关的临床情况下。由于贫血的幼儿通常能够利用仍然较大的红髓腔,因此EMH在成人中更为常见。我们观察到两名年轻女孩,她们的骨髓无法产生足够的血液制品,而是发生了EMH,其中一名有文献记载且很少报道的肾脏受累情况。以下对她们进行描述。

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本文引用的文献

1
Renal enlargement in thalassemia major.重型地中海贫血中的肾脏增大。
Radiology. 1971 Sep;100(3):645-8. doi: 10.1148/100.3.645.
2
Ultrasound appearance of extramedullary hematopoiesis.
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3
Infantile myelofibrosis with nephromegaly secondary to myeloid metaplasia.
Clin Pediatr (Phila). 1991 Jan;30(1):59-61. doi: 10.1177/000992289103000111.
4
Ultrasound and computed tomographic appearance of extramedullary hematopoiesis encasing the renal pelvis.
包绕肾盂的髓外造血的超声及计算机断层扫描表现。
J Clin Ultrasound. 1991 May;19(4):238-40. doi: 10.1002/jcu.1870190411.
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Myelofibrosis-myeloid metaplasia in childhood.儿童期骨髓纤维化-髓样化生
Pediatrics. 1975 Jun;55(6):861-5.