Vianna Raul N G, Pena Rafael, Muralha Acácio, Muralha Lília, Muranaka Eduardo
Department of Ophthalmology, Fluminense Federal University, Rio de Janeiro, Brazil.
Int Ophthalmol. 2004 Jan;25(1):23-6. doi: 10.1023/b:inte.0000018525.92811.e4.
Most patients who develop metastatic carcinoma to the choroid are managed by local radiation or chemotherapy. Since transpupillary thermotherapy (TTT) is currently gaining attention as an optional treatment for choroidal melanomas and hemangiomas, we sought to determine whether TTT is suitable for treatment of solitary choroidal metastasis at the posterior pole.
We report on a patient with decreased vision due to a serous macular detachment in a eye with a solitary choroidal metastasis from breast carcinoma, who was managed by TTT.
After two months of follow up, total re-absorption of the serous macular detachment was achieved and the patient recovered full visual acuity in the treated eye. The choroidal mass became atrophic and hyperpigmentation of the retinal pigment epithelium and retinal folds in the macular region were observed. After six months of TTT, the ocular picture remained unchanged.
TTT can be considered an acceptable therapeutic option for solitary choroidal metastasis associated with serous retinal detachment.
大多数发生脉络膜转移癌的患者采用局部放疗或化疗进行治疗。由于经瞳孔温热疗法(TTT)目前作为脉络膜黑色素瘤和血管瘤的一种可选治疗方法而受到关注,我们试图确定TTT是否适用于治疗后极部孤立性脉络膜转移瘤。
我们报告了一名因乳腺癌孤立性脉络膜转移导致一只眼睛发生浆液性黄斑脱离而视力下降的患者,该患者接受了TTT治疗。
经过两个月的随访,浆液性黄斑脱离完全吸收,患眼视力完全恢复。脉络膜肿物萎缩,观察到黄斑区视网膜色素上皮色素沉着和视网膜皱褶。TTT治疗六个月后,眼部情况保持不变。
TTT可被视为与浆液性视网膜脱离相关的孤立性脉络膜转移瘤的一种可接受的治疗选择。