Kroll Martin H, Styer Patricia E, Vasquez Delmiro Anthony
Department of Clinical Chemistry, Dallas VA Medical Center, Dallas, Tex 75216, USA.
Arch Pathol Lab Med. 2004 May;128(5):544-8. doi: 10.5858/2004-128-544-CVPRTP.
Since 1988, the College of American Pathologists has been offering materials for calibration verification coupled with the surveys for linearity, called the linearity (LN) surveys.
To determine whether successful completion of the College of American Pathologists LN surveys provides a benefit in terms of improved proficiency testing (PT) performance.
In this study, we used information from LN surveys LN1/2, LN3, and LN5 and from the PT surveys C, Z, and K administered and analyzed in the year 2000. For the PT data, we calculated 4 measures of performance: passing PT, results exceeding 2 SDs, sum of absolute SD intervals, and the absolute sum of SD intervals. For the LN data, we classified laboratories as participants versus nonparticipants in LN surveys and by whether or not LN survey performance was successful.
LN enrollees had fewer unacceptable PT results than did nonenrollees. Additionally, for many analytes there was a significant positive association between LN performance and PT performance.
For most analytes studied, there was strong evidence linking performance on PT surveys with performance on LN surveys. Eight of 13 analyses (62%) demonstrated improved performance with successful calibration verification.
自1988年以来,美国病理学家学会一直在提供用于校准验证的材料以及线性度调查,即线性度(LN)调查。
确定成功完成美国病理学家学会的LN调查是否能在提高能力验证(PT)表现方面带来益处。
在本研究中,我们使用了2000年进行并分析的LN调查LN1/2、LN3和LN5以及PT调查C、Z和K的信息。对于PT数据,我们计算了4种表现指标:通过PT、结果超过2个标准差、绝对标准差区间总和以及标准差区间的绝对总和。对于LN数据,我们根据实验室是否参与LN调查以及LN调查表现是否成功将实验室分为参与者和非参与者。
参与LN调查的人员的PT结果不可接受的情况比未参与者少。此外,对于许多分析物,LN表现与PT表现之间存在显著的正相关。
对于大多数研究的分析物,有强有力的证据表明PT调查表现与LN调查表现之间存在关联。13项分析中的8项(62%)表明成功的校准验证可提高表现。