Nickerson H James, Silberman Teresa, Jacobsen F Stig, Krawisz Bruce R, Maki Hope S, Arndt Carola A S
Department of Pediatrics, Marshfield Clinic, WI 54449, USA.
J Pediatr Hematol Oncol. 2004 Apr;26(4):233-5. doi: 10.1097/00043426-200404000-00004.
Alveolar soft-part sarcoma (ASPS) is a very rare malignant tumor, usually of the extremities, and is seen most often in adolescents and young adults. Surgical excision of the primary and pulmonary metastases has resulted in prolonged survival in some patients, but adjuvant radiation and/or chemotherapy are generally thought to be ineffective. The authors describe a 13-year-old patient with ASPS of an extremity who presented with multiple bilateral pulmonary metastases at diagnosis. Following intensive multiagent chemotherapy, pulmonary metastases showed in vivo evidence of tumor death. The patient has remained disease-free for 10 years following treatment.
肺泡软组织肉瘤（ASPS）是一种非常罕见的恶性肿瘤，通常发生于四肢，最常见于青少年和年轻成年人。对原发灶和肺转移灶进行手术切除已使部分患者生存期延长，但一般认为辅助放疗和/或化疗无效。作者描述了一名13岁患有四肢ASPS的患者，诊断时出现双侧多发肺转移。经过强化多药化疗后，肺转移灶显示出肿瘤死亡的体内证据。该患者治疗后已无病生存10年。
