Panopoulos P
Department of Endodontics, University of Athens Dental School, Greece.
Proc Finn Dent Soc. 1992;88 Suppl 1:155-60.
The mechanisms by which pain develops in carious teeth are poorly understood. The variability of dentin and pulp responses to carious attack is probably the cause for the variations in the pain symptoms presented by patients. This article is a review of the available data regarding the changes that dentin and pulp undergo in carious teeth. Such changes are discussed in relation to their possible influence on intradental sensory nerve excitability. Special emphasis is given to the various bacterial metabolites produced and accumulated in carious dentin and their ability to modulate pain symptoms from carious teeth.
龋齿疼痛产生的机制目前还知之甚少。牙本质和牙髓对龋病侵袭反应的变异性可能是患者出现不同疼痛症状的原因。本文综述了有关龋病牙齿中牙本质和牙髓所发生变化的现有数据。将讨论这些变化对牙内感觉神经兴奋性可能产生的影响。特别强调了在龋坏牙本质中产生和积聚的各种细菌代谢产物及其调节龋病牙齿疼痛症状的能力。
