Mohan Kanwar, Saroha Vandana, Sharma Ashok
Squint Clinic, Grewal Eye Institute, Chandigarh, India.
J Pediatr Ophthalmol Strabismus. 2004 Mar-Apr;41(2):89-95. doi: 10.3928/0191-3913-20040301-08.
To investigate the effectiveness of full-time occlusion therapy in treating amblyopia in 11- to 15-year-old children and to determine its lasting results.
Fifty-five compliant children 11 to 15 years old who had amblyopia were treated with full-time (during all waking hours) occlusion of their good eye until no further improvement in the visual acuity of their amblyopic eye was observed on 3 consecutive monthly follow-up examinations. After this, part-time (4 hours per day) occlusion therapy was used randomly in 24 of 55 patients for 3 to 6 months for maintenance of the final visual acuity. Snellen visual acuity and its logMAR equivalent were recorded before treatment, at the cessation of full-time occlusion therapy, and on the most recent examination.
All 55 of the patients had improved visual acuity after treatment. The mean improvement was 0.46 logMAR unit (4.6 Snellen lines). Thirty-two of the patients had a mean follow-up of 17.6 months after the cessation of full-time and maintenance occlusion therapy. Twenty-nine (91%) of the 32 patients maintained improved visual acuity, whereas 3 (9%) exhibited a regression in visual acuity. Maintenance occlusion therapy did not have a significant stabilizing effect on the improved visual acuity.
Compliant, full-time occlusion effectively improves acuity in children 11 to 15 years old who have amblyopia due to strabismus, anisometropia, or both. Most older patients have lasting improvement with or without maintenance patching.
研究全职遮盖疗法治疗11至15岁儿童弱视的有效性,并确定其长期效果。
55名年龄在11至15岁、依从性良好的弱视儿童接受了好眼全职(清醒时全程)遮盖治疗,直至连续3个月的每月随访检查中弱视眼视力无进一步改善。此后,55名患者中的24名被随机采用兼职(每天4小时)遮盖疗法3至6个月,以维持最终视力。在治疗前、全职遮盖疗法结束时以及最近一次检查时记录Snellen视力及其logMAR等效值。
所有55名患者治疗后视力均有改善。平均改善为0.46 logMAR单位(4.6 Snellen行)。32名患者在全职和维持遮盖疗法结束后平均随访17.6个月。32名患者中有29名(91%)维持了视力改善,而3名(9%)视力出现了退步。维持遮盖疗法对改善后的视力没有显著的稳定作用。
依从性良好的全职遮盖疗法能有效提高11至15岁因斜视、屈光参差或两者兼而有之导致弱视的儿童的视力。大多数大龄患者无论是否进行维持性遮盖都有持久的视力改善。