新型选择性β2-肾上腺素能受体激动剂5-(1-羟基-2-异丙氨基丁基)-和5-(1-羟基-2-乙氨基丁基)-8-羟基喹啉盐酸盐（OPC-2009和OPC-2030）与环磷酸腺苷浓度 - Suppr | 超能文献

New selective beta2-adrenoreceptor stimulants 5(1-hydroxy-2-isopropylaminobutyl)- and 5-(1-hydroxy-2-ethylaminobutyl)-8-hydroxycarbostyril hydrochlorides (OPC-2009 and OPC-2030) and cyclic AMP concentration.

作者信息

Takayanagi I, Kondo N, Yamashita H, Hongo T, Takagi K

出版信息

J Pharm Pharmacol. 1977 Mar;29(3):187-9. doi: 10.1111/j.2042-7158.1977.tb11284.x.

DOI:10.1111/j.2042-7158.1977.tb11284.x

PMID:15090

Abstract

摘要

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New selective beta2-adrenoreceptor stimulants 5(1-hydroxy-2-isopropylaminobutyl)- and 5-(1-hydroxy-2-ethylaminobutyl)-8-hydroxycarbostyril hydrochlorides (OPC-2009 and OPC-2030) and cyclic AMP concentration.新型选择性β2-肾上腺素能受体激动剂5-(1-羟基-2-异丙氨基丁基)-和5-(1-羟基-2-乙氨基丁基)-8-羟基喹啉盐酸盐（OPC-2009和OPC-2030）与环磷酸腺苷浓度

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2

The beta-adrenoceptor stimulant properties of OPC-2009 on guinea-pig isolated tracheal, right atrial and left atrial preparations.OPC - 2009对豚鼠离体气管、右心房和左心房标本的β - 肾上腺素能受体刺激特性。

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3

Assessment of the selectivity of OPC-2009, a new beta2-adrenoceptor stimulatn, by the use of the blood-perfused trachea in situ and of the isolated blood-perfused papillary muscle of the dog.通过使用原位血液灌注气管和犬离体血液灌注乳头肌来评估新型β2肾上腺素能激动剂OPC-2009的选择性。

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4

Effect of trimetoquinol on the cyclic AMP level in the tracheal muscle of guinea-pig.曲美托喹对豚鼠气管肌肉中环磷酸腺苷水平的影响。

Biochem Pharmacol. 1974 Nov 15;23(22):3213-6. doi: 10.1016/0006-2952(74)90608-x.

5

Studies on beta-adrenoceptors mediating changes in mechanical events and adenosine 3',5'-monophosphate levels. Guinea-pig trachea.

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Comparison of the action of BD 40 A and some other beta-adrenoceptor stimulants on the isolated trachea and atria of the guinea pig.BD 40 A与其他一些β-肾上腺素能受体兴奋剂对豚鼠离体气管和心房作用的比较。

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The use of functional antagonism to determine whether beta-adrenoceptor agonists must have a lower efficacy than isoprenaline to be trachea-atria selective in vitro in guinea-pigs.利用功能拮抗作用来确定β-肾上腺素能受体激动剂在豚鼠体外实验中对气管-心房具有选择性时，其效能是否必定低于异丙肾上腺素。

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8

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9

Studies on the effects of enantiomers of soterenol, trimetoquinol and salbutamol on beta adrenergic receptors of isolated guinea-pig atria and trachea.索特雷诺、曲美托喹和沙丁胺醇对豚鼠离体心房和气管β肾上腺素能受体的对映体效应研究。

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10

A comparison of the beta-adrenoreceptor stimulant properties of isoprenaline, with those of orciprenaline, salbutamol, soterenol and trimetoquinol on isolated atria and trachea of the guinea pig.异丙肾上腺素与奥西那林、沙丁胺醇、索布特罗和曲美托喹啉对豚鼠离体心房和气管的β-肾上腺素能受体刺激特性比较。

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引用本文的文献

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Pre- and post-junctional actions of procaterol, a beta 2-adrenoceptor stimulant, on dog tracheal tissue.β2肾上腺素能受体激动剂丙卡特罗对犬气管组织的接头前和接头后作用

Br J Pharmacol. 1988 Sep;95(1):268-74. doi: 10.1111/j.1476-5381.1988.tb16573.x.

2

Relaxing actions of procaterol, a beta 2-adrenoceptor stimulant, on smooth muscle cells of the dog trachea.β2肾上腺素能受体激动剂丙卡特罗对犬气管平滑肌细胞的舒张作用。

Br J Pharmacol. 1988 Jan;93(1):199-209. doi: 10.1111/j.1476-5381.1988.tb11422.x.