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射频诱导收缩后的固定是否会影响胶原组织的生物力学特性?一项兔体内研究。

Does immobilization after radiofrequency-induced shrinkage influence the biomechanical properties of collagenous tissue? An in vivo rabbit study.

作者信息

Pötzl Wolfgang, Heusner Till, Kümpers Philipp, Marquardt Björn, Steinbeck Jörn

机构信息

Department of Orthopaedics, University Hospital Münster, Münster, Germany.

出版信息

Am J Sports Med. 2004 Apr-May;32(3):681-7. doi: 10.1177/0363546503261699.

DOI:10.1177/0363546503261699
PMID:15090385
Abstract

BACKGROUND

Despite widespread use of radiofrequency-induced shrinkage of collagenous tissue, there have been no animal studies on the effects of postoperative immobilization on the biomechanical behavior of shrunken tissue.

PURPOSE

To examine the role of postoperative immobilization after radiofrequency-induced shrinkage, with special emphasis on the biomechanical properties of shrunken collagenous tissue.

STUDY DESIGN

Controlled laboratory study.

METHODS

One patellar tendon of 66 New Zealand White rabbits was shrunk. Six rabbits were sacrificed immediately after surgery. Twenty rabbits were not immobilized, twenty were immobilized for 3 weeks, and twenty were immobilized for 6 weeks. The biomechanical parameters failure strength, stiffness, and relaxation were tested.

RESULTS

Nine weeks after surgery, biomechanical parameters were still low compared to control tendons. Shrunken tendons did not reach levels of normal tissue at any time after surgery, regardless of whether the animals had been immobilized. According to time-related development, all biomechanical parameters had the lowest levels 3 weeks after surgery. Immobilized tendons demonstrated a better and faster recovery than nonimmobilized tendons compared to the immediate postoperative level.

CONCLUSION

Postoperative immobilization supports recovery of biomechanical properties after shrinkage. Despite immobilization, biomechanical properties of shrunken tissue did not completely reach levels of normal tissue.

CLINICAL RELEVANCE

Careful rehabilitation is imperative after radiofrequency-induced shrinkage. This animal model supports an immobilization period of at least 6 weeks after surgery.

摘要

背景

尽管射频诱导胶原组织收缩已被广泛应用,但尚无关于术后固定对收缩组织生物力学行为影响的动物研究。

目的

研究射频诱导收缩术后固定的作用,特别关注收缩胶原组织的生物力学特性。

研究设计

对照实验室研究。

方法

对66只新西兰白兔的一条髌腱进行收缩处理。6只兔子在术后立即处死。20只兔子不进行固定,20只兔子固定3周,20只兔子固定6周。测试生物力学参数破坏强度、刚度和松弛度。

结果

术后9周,与对照肌腱相比,生物力学参数仍较低。无论动物是否固定,收缩后的肌腱在术后任何时候都未达到正常组织水平。根据时间相关的发展,所有生物力学参数在术后3周时最低。与术后即刻水平相比,固定的肌腱比未固定的肌腱恢复得更好、更快。

结论

术后固定有助于收缩后生物力学性能的恢复。尽管进行了固定,收缩组织的生物力学性能并未完全达到正常组织水平。

临床意义

射频诱导收缩术后必须进行仔细的康复治疗。该动物模型支持术后至少固定6周。

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