Wetzels J F, Burke T J, Schrier R W
Department of Medicine, University of Colorado School of Medicine, Denver.
Ren Fail. 1992;14(3):327-32. doi: 10.3109/08860229209106637.
Studies in heart, liver, and kidney have provided evidence that calcium is an important factor in cell injury. Calcium channel blockers are used with increasing frequency in ischemic and toxic renal failure. In this review the available data on the effects of calcium channel blockers in animal models of ischemic renal failure are presented and possible mechanisms of protective actions are discussed.
对心脏、肝脏和肾脏的研究已提供证据表明，钙是细胞损伤中的一个重要因素。钙通道阻滞剂在缺血性和中毒性肾衰竭中的使用频率越来越高。在这篇综述中，我们展示了关于钙通道阻滞剂在缺血性肾衰竭动物模型中作用的现有数据，并讨论了其可能的保护作用机制。
